Mastisol® Liquid Adhesive

Mastisol Product Family

What is Mastisol?

Mastisol is a liquid medical adhesive used to secure dressings, tapes, and certain medical devices over an extended period of time.

Use of Mastisol offers the following benefits:

  • Reduced likelihood of dressing displacement and device dislodgement⁴
  • Minimized risk of device-related infection by creating a lasting occlusive barrier.⁵
  • Improved nurse efficiency with reduced time associated with unplanned dressing changes.⁸
  • Versatility to improve the adhesive power of a variety of adhesive tapes, dressings and, devices.³
  • Compatible with chlorhexidine gluconate (CHG)⁷
  • Low risk of adverse reactions and latex-free⁴

Instructions for Use

Security comes in four easy steps:

Crack: Place an individual sterile vial blister pack on a hard surface with the label facing down. Gently apply pressure to the vial through the blister pack to crush the inner ampule to release Mastisol.

Peel: Peel back the lid of the blister pack and remove the vial using aseptic technique.

Apply: Turn the vial upside-down to dispense Mastisol onto the skin in a half-inch wide line.
Apply Mastisol to the outside border of where the dressing will be placed, avoiding the area immediately surrounding the catheter insertion site.
Allow Mastisol to dry completely, for approximately 20–30 seconds.

Dress: Per facility protocol, apply the dressing to the skin, ensuring edges are in contact with Mastisol.

For best results, use Detachol Adhesive Remover for removal.

Download IFU Pamphlet

Product Resources

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    Improve Patient Outcomes

    Use of Mastisol reduces likelihood of dressing displacement and device dislodgement¹²³⁴ creating a lasting occlusive barrier that minimizes risk of infection.⁵⁶⁷ Mastisol is non-water soluble and secures even in moist or moisture-prone areas and is compatible with Chlorhexidine Gluconate⁷

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    Increase Quality

    Mastisol promotes compliance with CDC guidelines, reducing workflow disruption.¹²³⁴ It is clinically-proven to improve the adhesive power of a variety of different adhesive tapes/dressings.³

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    Reduce Cost

    Mastisol can reduce product waste due to fewer unscheduled dressing changes resulting in overall supply cost savings and recovered nursing time.

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    Operating Room

    Wound Closure Strip Securement, ET Tube Securement, Sterile Field Drapes

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    Intensive Care Units

    Vascular Access Device Dressing Securement, ET Tube & NG Tube Securement, Fecal Management Bag & Foley Anchor Securement

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    Hematology/Oncology

    Vascular Access Device Dressing Securement, Wound Dressing Securement

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    Emergency Room

    Wound Closure Strip Securement, Wound Dressing Securement, Chest Tube Securement

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    Pediatrics

    Vascular Access Device Dressing Securement, Wound Dressing Securement, ET Tube & NG Tube Securement

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    Respiratory Therapy

    ET Tube & NG Tube Securement

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    Vascular Access Team

    Vascular Access Device Dressing Securement

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    Wound Ostomy

    Ostomy Appliance Securement, Wound Dressing Securement, NPWT Drape Securement

Download the latest data and product information surrounding Mastisol Liquid Adhesive.

Free On-Demand Webinars featuring some of the finest thought-leaders in healthcare specialties such as Infection Prevention, Vascular Access, Surgical Care and more.

Here you will find a collection of issues we think acute caregivers want and need to know about. We understand the challenges faced by hospitals in the US today, and we want to deliver practical information that can be applied to your daily practice.

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Ordering Information

Product SKUs 0496-0523-48 0496-0523-15 0496-0523-16 0496-0523-06
Product 48 x 2/3 mL Sterile Vial, Box 15 mL, Bottle 15 mL, Spray Bottle 2 oz, Bottle
Packer Qty 1 12 12 12

Testimonials

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David M

"As a healthcare provider with extensive experience in vascular access, I have consistently relied on Mastisol for improving dressing adherence. In my practice, we often face challenges with dressings coming loose, especially in high-moisture areas or with active patients. Since incorporating Mastisol, we've seen a significant reduction in compromised dressings . It provides a reliable barrier that ensures the dressing stays secure for extended periods, which is crucial for preventing infections and maintaining site integrity. Mastisol has become a staple in my practice for its superior adhesive properties, ensuring that dressings stay in place even under challenging conditions."

– David M., Kissimmee, FL

Denaye B

"I have been using Mastisol for years and it is the "cherry on top" to complete a perfect, secure PICC dressing. Keeping any dressing on for 7 days in pediatrics is always a challenge but with the use of Mastisol, we have had great success in reaching this goal!"

– Denaye B., Akron, OH

Lyla H

"The edges of the dressings have been intact after using the product, reduce our frequency to need to change dressings, giving staff more time to do other tasks, staying within the INS guidelines, reducing CLABSI."

– Lyla H., San Francisco, CA

Brittany G

"We began using Mastisol on our CVC dressings after we found they were not lasting a full 7 days between dressing changes. We initially started on only 2 intensive care units of our level 1 trauma center. After seeing an increase in dressing adherence and decrease in CLABSI, we now have a dedicated dressing change team using Mastisol exclusively on all CVC dressing changes in the entire hospital."

– Brittany G., Murray, UT

Buerkley O

"In Ambulatory, We use Mastisol for patients that will be admitted or go home with a continuous infusion going through their central line. The product works incredibly well and definitely prevents issues with the dressing when patients go home and return for disconnect."

– Buerkley O., Chicago, IL

Desiree W

"We had elevated rates of CLABSIs on our hem onc and stem cell units prior to mastisol use. We were also having significant issues with our dressings lasting 7 days. Now we have limited CLABSIs and our dressings are lasting significantly longer."

– Desiree W., Chicago, IL

Mason F

"With our initial evaluation of Mastisol, we targeted high risk CVAD dressings in an area with frequent repeat PRN loose dressing changes. Prior to Mastisol, we averaged 23 repeat CVAD PRN dressing changes due to loose dressings (data collected January-May). The first month of evaluation (June), this number was reduced to 5 repeat CVAD PRN dressing changes. We look forward to implementing this throughout our facility and seeing a further decrease in repeat CVAD PRN loose dressing changes."

– Mason F., Fort Worth, TX

Traci S

“With the use of Mastisol our central lines placed at the jugular site have remained intact longer than without using the product”

– Traci S., Infection Control Coordinator, Flint, MI

Diana B

“Mastisol was the only product able to hold the system on the patient…it was easy to use and did not burn or hurt the patient.”

– Diana B., RN, Falls Church, VA

Lori M

“This product is really making a difference in patient care. The tape {used to secure the NG tube} kept sliding down the patient’s nose {due to their oily skin and} put the patient at risk of aspiration. When Mastisol was used…problem solved.”

– Lori M., RN, Dearborn, MI

Frank S

“Allows for fewer dressing changes, keeps CVAD dressings intact longer then when product is not utilized.”

–Frank S., Houston, TX

Beverly B

“I have had numerous years of experience with Mastisol. It is easy to use and has superior adhesive qualities. I have never heard any complaints about the product, either from practitioners or patients.”

– Beverly B., Clinical Educator, Phoenix, AZ

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From the Eloquest Healthcare Blog

[1]Deneau J, Craig A. Nursing Survey Reveals Novel Strategy in Assisting Adherence to Best Practices of CVC Dressing Management. Poster presented at: Institute for Healthcare Improvement National Forum, December 8-11, 2013.

[2]Pullen D. Quality Improvement Initiative to Improve Dressing Adherence Reveals Improved Dressing Adherence Observations on a Before- After Analysis. Poster presented at: AVA Annual Scientific Meeting, September 7-10, 2014.
[3]Patel N. The influence of tape type and of skin preparation on the force required to dislodge angiocatheters. Can J Anaesth. 1994;41:8:738-741

[4]Lesesne CB. The postoperative use of wound adhesives: gum mastic versus benzoin, USP.J Dermatol Surg Onc. 1992;18(11):990.

[5]Timsit J. et al. Dressing disruption is a major risk factor for catheter-related infections. Crit Care Med. 2012;40(6):1701-1714.

[6]Browne B, Moffo H. Quality improvement initiative results in fewer dressing disruptions and improved adherence to best practices. Presented at: Greater Cincinnati AACN Chapter, 28th Annual Trends in Critical Care Conference, April 8, 2016.

[7]Ryder M, Duley C. Evaluation of compatibility of a gum mastic liquid adhesive and liquid adhesive remover with an alcoholic chlorhexidine gluconate skin preparation. J Infus Nurs. 2016;40(4):245-252.

[8]Nelson Squires E, Bruggeman S. Use of gum mastic medical adhesive to maintain central venous access device dressing integrity. Presented at: Association for Vascular Access Annual Scientific Meeting, October 4-7, 2019.